The Caucasus Journal of Medical and Psychological Sciences https://caucasusjournal.com/index.php/CJMPS <p><strong>“The Caucasus Journal of Medical and Psychological Sciences” </strong><strong>(CJMPS</strong>) is a peer-reviewed journal publishing empirical, clinical and theoretical research spanning the entire spectrum of the science of medicine, biomedical, and pharmaceutical sciences, sports medicine and rehabilitation and their clinical, therapeutic studies; the latest findings on topics from cognitive, social, developmental, and health psychology, behavioral neuroscience and biopsychology; achievements in the field of medical and psychological education, systematic reviews and meta-analyses; measurements in psychology and medicine, articles on the philosophy of medicine and psychology, psycholinguistics, medical linguistics (Lexico-grammatical, linguocultural and communicative aspects of the language of medicine and psychology), as well as the relationship of legal and moral aspects of professional medical activity, medical law. Particular importance in the publication policy of the journal is given to the regional peculiarities of the development, course, diagnosis, and treatment of diseases occurring in various regions of the Caucasus and neighboring countries, including sanatorium treatment and rehabilitation of patients, as well as issues of the history of medicine and psychology in the Caucasus and neighboring countries. CJMPS is founded in 2023. There are two versions of the Journal – printed and electronic. (6 issues per year, online and printed, since 2024 – four issues per year). Articles are accepted for publication in Russian or in English. The Abstracts – in Georgian, Russian, and English (translated by the staff of the Journal). The articles are added to the website as they complete production. Each article published in the Journal is assigned its unique DOI. This ensures the article will be immediately and permanently free to access by everyone. CJMPS adheres to the principle of free access and exists at the expense of authors' payments for publications. CJMPS has a publication fee ($350) which needs to be met by the authors or their research funders for each article published open access. The journal provides open access to the full texts of scientific articles immediately after their publication. Open Access Publishing Fee is payable only after the journal article is accepted for publication. Submitted manuscripts must not be under consideration or published elsewhere or concurrently submitted to another journal; manuscripts that were previously published in other publications, as well as in the form of online preprints, are not accepted for publication.</p> <p>Manuscripts are accepted for consideration by e-mail: <strong><a href="mailto:[email protected]">[email protected]</a></strong></p> <p><strong>Archiving:</strong></p> <p><span style="font-size: 0.875rem;">National Parliamentary Library of Georgia </span></p> <p><span style="font-size: 0.875rem;">National Science Library of Georgia </span></p> <p><strong>pISSN</strong>: 2720-877X</p> <p><strong>eISSN</strong>: 2720-8788</p> <p><strong>Contact details</strong>: +995 592 401 278</p> <p><strong>Founder/Publisher</strong>: Zaza A. Kekelia</p> <p>Published by the <strong>“Foundation for the Protection of Social Pediatrics”</strong> with the participation of the Editorial Board of CJMPS to support medical and psychological sciences</p> The Social Pediatrics Protection Fund en-US The Caucasus Journal of Medical and Psychological Sciences 2720-877X An Artificial Intelligence Model for an Emerging New Paradigm in Medical Education: Which Model of Psychology Should Be Chosen? https://caucasusjournal.com/index.php/CJMPS/article/view/31 <p>Based on the tasks and models of intellectual communication, the article considers the problem of the organization of psychology as a knowledge system. The operational model of intelligence proposed by Piaget is considered in detail and the productivity of using this model, which is an analogue of idealized design, is justified. Identical to Piaget’s definition, intelligence is described as the ability of a psychological object to imagine a certain future, target reality in its imagination, to realize the existing reality, formulate transition operations and make the transition using finite resources and in a finite period of time. Using several examples, the issues of the complexity of intelligent communication with messages of clear and fuzzy logic are considered, the concepts of intelligent noise and a useful signal are introduced. It is proposed, using the approaches of operations research, to begin to carry out research on intellectual operations for their optimization when used in educational systems. The model of idealized design of education is considered and the plan of productive intellectual communication of psychology with exact and natural sciences for education is discussed.</p> L. A. Gheonjian Copyright (c) 2024 The Caucasus Journal of Medical and Psychological Sciences 2024-10-21 2024-10-21 2 1-2 1 21 10.61699/cjmps-v2-i1-2-p1-21 The Second Tiflis Classical Male Gymnasium Named After Grand Duke Mikhail Nikolaevich: Joseph Drboglav, Georgi Ghekhtman and High School Students Graduated In 1900 https://caucasusjournal.com/index.php/CJMPS/article/view/32 <p>The article describes the formation of the gymnasium system and the growing interest in gymnasiums and higher education in the middle of the 19th century in the Caucasus. Special attention is paid to the history of establishing the Second Tiflis Male Classical Gymnasium and the activity of the director and teacher of ancient languages, J.F. Drboglav (Droboglav), and its brilliant graduating class of 1900. Many graduates have gained worldwide fame: Mikhail Asatiani, Vladimir Ern, Pavel Florensky, Irakli Tsereteli, Alexander Yelchaninov (also spelled Elchaninov), etc. The teacher of history, G.N. Ghekhtman, was an intelligent, competent, talented, and inspired teacher. He had a great influence on the development of independent thinking skills and interest in serious research among high school students. Teachers and graduates of the gymnasium have made a great contribution to the development of both regional and domestic science, culture, and socio-political thought. Teachers and graduates of the gymnasium have made a great contribution to the development of both regional and domestic science, culture, and socio-political thought. At Kharkiv University, the destinies of two graduates of the 2nd Tiflis Classical Male Gymnasium crossed: E.K. Redin (1884), associate professor of the Department of Fine Arts History and Theory at Kharkiv University, and a student of Kharkiv University, D.D. Kilosanidze (1900). In 1907, D.D. Kilosanidze was awarded a gold medal for an essay on the history of art: “Gelati Monastery and its Art Monuments.” Focusing on the history of the establishment of the 2nd Tiflis Classical Gymnasium and the fate of its high school students graduated in 1900—the most outstanding in the history of the gymnasium gives food for thought in search of the most adequate ways to modernize education aimed at forming the intellectual potential of the younger generation, improving the educational level of young people, and developing their professional competencies that meet modern requirements towards the development of the economic, social, and humanitarian spheres of society.</p> N. V. Melkadzе N. B. Kobakhidze B. G. Saria Copyright (c) 2024 The Caucasus Journal of Medical and Psychological Sciences 2024-10-21 2024-10-21 2 1-2 22 49 10.61699/cjmps-v2-i1-2-p22-49 The Efficacy and Safety of Topical Cyclosporine A and its Generic Equivalency Depores Eye Drops in The Treatment of Dry Eye Disease https://caucasusjournal.com/index.php/CJMPS/article/view/33 <p>Dry eye disease (DED) is a complex condition that can result in significant vision complications. Analyzing systematic reviews of DED treatment contributes to selecting the most effective and safe drug. This review examines the efficacy of cyclosporine A and the generic Depores ophthalmic emulsion cyclosporine 0.05% (cyclosporine 0.05%, Deva Pharmaceuticals, Turkey) in the treatment of DED. A search for scientific information in PubMed, PubMed Central, The Cochrane Library, Google Scholar databases, and the Internet was carried out using keywords: dry eye disease, Cyclosporine A, Ikervis, Restasis, generic cyclosporine 0.05% ophthalmic emulsion, Depores. The literature cited in scientific articles was also reviewed. The analysis of scientific articles allowed us to conclude about the efficacy of the Restasis–Depores generic (cyclosporine 0.05%, Deva Pharmaceuticals, Turkey) for the treatment of patients with DED who have not yet had access to this treatment. Depores is now available in Georgia, bringing a novel treatment option to patients with severe DED. The study revealed a small number of clinical studies evaluating the efficacy and safety of generic cyclosporine 0.05% ophthalmic emulsion. Given the scarcity of research articles on this generic, it is necessary to study the results of its use in the treatment of DED in Georgia, which will help improve the quality of life with a diagnosis of dry eye.</p> Medea V. Papava Nana J. Gaprindashvili Copyright (c) 2024 The Caucasus Journal of Medical and Psychological Sciences 2024-10-21 2024-10-21 2 1-2 50 68 10.61699/cjmps-v2-i1-2-p50-68 School of Sanitary Instructors of the Transcaucasian Military District (Front) During World War II (1941-1945) https://caucasusjournal.com/index.php/CJMPS/article/view/34 <p>Based on archival materials and literary sources, the article recreates the general picture of the activities of the School of Sanitary Instructors of the Transcaucasian Military District (Front), located in the capital of the Georgian SSR, Tbilisi, during the Great Patriotic War. The purposeful work of school commanders and political workers aimed at improving the quality of cadets’ studies and strengthening military discipline is shown. Brief biographical information about the leadership of the school is provided, and the exploits of an outstanding graduate of the school, Hero of the Soviet Union Abdullayev Samad Gamil Oglu, are described.</p> I. V. Kartashev A. V. Kartashev Copyright (c) 2024 The Caucasus Journal of Medical and Psychological Sciences 2024-10-21 2024-10-21 2 1-2 69 78 10.61699/cjmps-v2-i1-2-p69-78 Factors Affecting Fertility in Modern Georgia https://caucasusjournal.com/index.php/CJMPS/article/view/35 <p>The article analyses the dynamics of the number of births and abortions, based on the data of the National Statistical Service “Geostat” (1990-2021) and the National Center for Disease Control and Public Health. In 1990, the total number of women in the population of Georgia was 2852.0 thousand, and the number of fertile age was 1362.0 thousand. In 2021, the total number of women decreased to 1932.0, and the number of women of fertile age to 822 thousand. The special birth rate index was calculated, based on which the main factors affecting the birth rate were analyzed. Within the article, the analysis of the involvement of women citizens of Georgia in migration processes was carried out. From 2014 to 2020, the number of women leaving the country, including those of fertility age, exceeded the number of arrivals. The article also discusses the main causes of the demographic crisis in Georgia and possible ways to overcome them.</p> N. Y. Kopaleishvili Copyright (c) 2024 The Caucasus Journal of Medical and Psychological Sciences 2024-10-21 2024-10-21 2 1-2 79 90 10.61699/cjmps-v2-i1-2-p79-90 Acute Acquired Comitant Esotropia https://caucasusjournal.com/index.php/CJMPS/article/view/36 <p>Acute acquired comitant esotropia (AACE) is an infrequent presentation of esotropia, characterized by sudden onset eye misalignment and diplopia. The purpose of this article is to review four cases of children diagnosed with AACE. We present 4 cases (children 610 years) of AACE. All of them suddenly developed diplopia and esotropia, with largeangle. After complete ophthalmological and neurological examinations in three cases out of four, strabismus surgery was conducted. In one case heterogenous neoplasm was detected and sent to an oncologist and neurosurgeon for evaluation and morphological verification. Bilateral medial rectus recession in two cases and unilateral recession of the medial rectus and resection of the lateral rectus in one case were performed. After strabismus surgery fully recovered binocular vision and was no longer noticeable diplopia. Neurological examinations and neuroimaging should be performed to exclude any potential intracranial disease. Surgery should be taken into consideration 6 months after the onset of the esotropia, if the deviation is stable. Strabismus surgery of AACE has good motor and sensory results and can successfully restore good binocular function The excessive use of smartphones may be associated with developing and increasing AACE.</p> Manana Kikolashvili Nana Kapanadze Nino Nikuradze Tamar Tkebuchava Badri Shengelia Copyright (c) 2024 The Caucasus Journal of Medical and Psychological Sciences 2024-10-21 2024-10-21 2 1-2 91 97 10.61699/cjmps-v2-i1-2-p91-97 Central Hypothyroidism Associated With Empty Sella: Literature Review and Case Report https://caucasusjournal.com/index.php/CJMPS/article/view/37 <p>Empty Sella Syndrome (ESS) is a rare case of sella turcica malformation, resulting in pituitary gland decrease. It may reveal itself through neurological symptoms, endocrine disorders, visual disturbances or incidental findings during imaging. The urgency of this problem has increased with the widespread use in the diagnosis of the non-invasive method of magnetic resonance imaging (MRI). It can be discovered as part of the investigation of the pituitary disorders, or as an incidental finding when imaging the brain. Practice shows that such patients rarely come with typical complaints thus an extended review of this case is needed to prompt suspicion and aid in the diagnosis of ESS. Few cases of empty sella associated with isolated thyroid-stimulating hormone (TSH) deficiency were published. We report a case of a 46 year-old woman with complaints: edema, dizziness, low blood pressure, hair loss, dry skin. Examinations were performed: ultrasound of the thyroid gland, TSH, FT4 (free thyroxine), FT3 (free triiodothyronine), anti TPO (Antibodies to thyroid peroxidase). Conclusion: patients with TSH, FT4, and FT3 deficiency, should undergo examinations to exclude empty sella as one of the reason of central hypothyroidism. According to the above mentioned the recommendation is to examine all the tropic hormones of the pituitary gland after diagnosing empty sella. Diagnosing central hypothyroidism associated with empty sella helps improving the knowledge and points to different clinical manifestation of empty sella syndrome.</p> Meri P. Rekvava Tamar T. Dundua Lali V. Javashvili Irakli V. Gakhokidze Nino T. Meladze Copyright (c) 2024 The Caucasus Journal of Medical and Psychological Sciences 2024-10-21 2024-10-21 2 1-2 98 107 10.61699/cjmps-v2-i1-2-p98-107